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	<title>Comments for 4mrcp.com</title>
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	<link>http://4mrcp.com</link>
	<description>.....Pass your MRCP exams with us.....</description>
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		<title>Comment on METABOLIC ALKALOSIS by Magoda</title>
		<link>http://4mrcp.com/?p=919&#038;cpage=1#comment-6772</link>
		<dc:creator>Magoda</dc:creator>
		<pubDate>Fri, 30 Oct 2009 20:41:12 +0000</pubDate>
		<guid isPermaLink="false">http://4mrcp.com/?p=919#comment-6772</guid>
		<description>In pure metabolic alkalosis, every 1 mEq/L increase in serum bicarbonate should result in a compensatory rise in Pco2 of 0.6mm Hg. This increase in CO2 should occur very quickly, and if more or less than 0.6 you to think of an associated respiratory abnormality. </description>
		<content:encoded><![CDATA[<p>In pure metabolic alkalosis, every 1 mEq/L increase in serum bicarbonate should result in a compensatory rise in Pco2 of 0.6mm Hg. This increase in CO2 should occur very quickly, and if more or less than 0.6 you to think of an associated respiratory abnormality.</p>
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	<item>
		<title>Comment on METABOLIC ALKALOSIS by Radwa</title>
		<link>http://4mrcp.com/?p=919&#038;cpage=1#comment-6771</link>
		<dc:creator>Radwa</dc:creator>
		<pubDate>Thu, 29 Oct 2009 10:37:12 +0000</pubDate>
		<guid isPermaLink="false">http://4mrcp.com/?p=919#comment-6771</guid>
		<description>Liddle’s syndrome is a rare autosomal dominant condition characterized by hypertension and hypokalaemic alkalosis. caused by sodium channels disorder in the distal tubules leading to increased reabsorption of sodium and potassium excretion.Treatment is with either amiloride or triamterene</description>
		<content:encoded><![CDATA[<p>Liddle’s syndrome is a rare autosomal dominant condition characterized by hypertension and hypokalaemic alkalosis. caused by sodium channels disorder in the distal tubules leading to increased reabsorption of sodium and potassium excretion.Treatment is with either amiloride or triamterene</p>
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	</item>
	<item>
		<title>Comment on Causes of hypercalcaemia by Naar</title>
		<link>http://4mrcp.com/?p=99&#038;cpage=1#comment-6769</link>
		<dc:creator>Naar</dc:creator>
		<pubDate>Tue, 27 Oct 2009 09:18:05 +0000</pubDate>
		<guid isPermaLink="false">http://4mrcp.com/?p=99#comment-6769</guid>
		<description>
Causes of primary hyperparathyroidism

• 80%: parathyroid solitary adenoma

• 15%: parathyroid hyperplasia

• 4%: parathyroid multiple adenoma

• 1%: parathyroid carcinoma
</description>
		<content:encoded><![CDATA[<p>Causes of primary hyperparathyroidism</p>
<p>• 80%: parathyroid solitary adenoma</p>
<p>• 15%: parathyroid hyperplasia</p>
<p>• 4%: parathyroid multiple adenoma</p>
<p>• 1%: parathyroid carcinoma</p>
]]></content:encoded>
	</item>
	<item>
		<title>Comment on Causes of hypercalcaemia by Magoda</title>
		<link>http://4mrcp.com/?p=99&#038;cpage=1#comment-6768</link>
		<dc:creator>Magoda</dc:creator>
		<pubDate>Tue, 27 Oct 2009 09:09:54 +0000</pubDate>
		<guid isPermaLink="false">http://4mrcp.com/?p=99#comment-6768</guid>
		<description>&lt;p&gt;In Post hyperparathyroidectomy.. we must give the patient vitamin D to avoid hypocalcemia and tetany.&lt;/p&gt;</description>
		<content:encoded><![CDATA[<p>In Post hyperparathyroidectomy.. we must give the patient vitamin D to avoid hypocalcemia and tetany.</p>
]]></content:encoded>
	</item>
	<item>
		<title>Comment on Hepatitis C by Nada</title>
		<link>http://4mrcp.com/?p=896&#038;cpage=1#comment-6767</link>
		<dc:creator>Nada</dc:creator>
		<pubDate>Tue, 27 Oct 2009 07:54:42 +0000</pubDate>
		<guid isPermaLink="false">http://4mrcp.com/?p=896#comment-6767</guid>
		<description>Interferon -alpha
 
Interferons (IFN) are cytokines released by leucocytes in response to &lt;strong&gt;&lt;em&gt;viral infections&lt;/em&gt;&lt;/strong&gt; and &lt;strong&gt;&lt;em&gt;neoplasia&lt;/em&gt;&lt;/strong&gt; • 
antiviral action useful in hepatitis B &amp; C, 
Anti-neoplasia actions as in: Kaposi&#039;s sarcoma, metastatic renal cell cancer, hairy cell leukaemia
 
• Side effects: flu-like symptoms and depression</description>
		<content:encoded><![CDATA[<p>Interferon -alpha<br />
 <br />
Interferons (IFN) are cytokines released by leucocytes in response to <strong><em>viral infections</em></strong> and <strong><em>neoplasia</em></strong> •<br />
antiviral action useful in hepatitis B &amp; C,<br />
Anti-neoplasia actions as in: Kaposi&#8217;s sarcoma, metastatic renal cell cancer, hairy cell leukaemia<br />
 <br />
• Side effects: flu-like symptoms and depression</p>
]]></content:encoded>
	</item>
	<item>
		<title>Comment on Causes of Chronic Liver Disease by Sorat</title>
		<link>http://4mrcp.com/?p=860&#038;cpage=1#comment-6765</link>
		<dc:creator>Sorat</dc:creator>
		<pubDate>Mon, 26 Oct 2009 21:59:35 +0000</pubDate>
		<guid isPermaLink="false">http://4mrcp.com/?p=860#comment-6765</guid>
		<description>&lt;p&gt; &lt;span lang=&quot;en-US&quot;&gt;&lt;strong&gt;Alcoholic hepatitis&lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;
&lt;p&gt;&lt;span lang=&quot;en-US&quot;&gt;History of drinking, presence of spider naevi and other signs of chronic liver disease &quot;as above&quot;. &lt;/span&gt;AST:ALT ratio &gt;2 and &lt;span lang=&quot;en-US&quot;&gt;resolution with alcohol abstinence.&lt;/span&gt;&lt;/p&gt;</description>
		<content:encoded><![CDATA[<p> <span lang="en-US"><strong>Alcoholic hepatitis</strong></span></p>
<p><span lang="en-US">History of drinking, presence of spider naevi and other signs of chronic liver disease &#8220;as above&#8221;. </span>AST:ALT ratio &gt;2 and <span lang="en-US">resolution with alcohol abstinence.</span></p>
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	</item>
	<item>
		<title>Comment on Causes of Chronic Liver Disease by Magoda</title>
		<link>http://4mrcp.com/?p=860&#038;cpage=1#comment-6764</link>
		<dc:creator>Magoda</dc:creator>
		<pubDate>Mon, 26 Oct 2009 18:55:07 +0000</pubDate>
		<guid isPermaLink="false">http://4mrcp.com/?p=860#comment-6764</guid>
		<description>&lt;p&gt; &lt;strong&gt;Risk factors of Hepatocellular carcinoma&lt;/strong&gt;&lt;/p&gt;
&lt;ol&gt;
&lt;li&gt;
&lt;p&gt;Hepatitis B and C&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Cirrhosis: “alcohol, haemochromatosis, primary biliary cirrhosis” all except wilson’s disease.&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Drugs: oral contraceptive pill, anabolic steroids&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Alpha-1 antitrypsin deficiency&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Hereditary tyrosinosis&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Porphyria cutanea tarda&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Glycogen storage disease&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;Aflatoxin&lt;/p&gt;
&lt;/li&gt;
&lt;/ol&gt;</description>
		<content:encoded><![CDATA[<p> <strong>Risk factors of Hepatocellular carcinoma</strong></p>
<ol>
<li>
<p>Hepatitis B and C</p>
</li>
<li>
<p>Cirrhosis: “alcohol, haemochromatosis, primary biliary cirrhosis” all except wilson’s disease.</p>
</li>
<li>
<p>Drugs: oral contraceptive pill, anabolic steroids</p>
</li>
<li>
<p>Alpha-1 antitrypsin deficiency</p>
</li>
<li>
<p>Hereditary tyrosinosis</p>
</li>
<li>
<p>Porphyria cutanea tarda</p>
</li>
<li>
<p>Glycogen storage disease</p>
</li>
<li>
<p>Aflatoxin</p>
</li>
</ol>
]]></content:encoded>
	</item>
	<item>
		<title>Comment on Causes of Chronic Liver Disease by Saady</title>
		<link>http://4mrcp.com/?p=860&#038;cpage=1#comment-6763</link>
		<dc:creator>Saady</dc:creator>
		<pubDate>Sat, 24 Oct 2009 21:27:50 +0000</pubDate>
		<guid isPermaLink="false">http://4mrcp.com/?p=860#comment-6763</guid>
		<description>Signs of chronic liver disease:
Clubbing
Leukonychia
Palmer erythema
Dupytren contracture
Astrexis
Juindice
Pallor
Xantholasma
Parotid enlargment
Fetor hepaticus
Bruising &amp; Ecchymosis
Spider nevi
Gynecomastia
Loss of  body hair (males)
Ascitis
Scratch marks
Caput medosa
Spleenomegaly
Liver may be enlarged or cirrhotic
Testicular atrophy
Lower limb edema
</description>
		<content:encoded><![CDATA[<p>Signs of chronic liver disease:<br />
Clubbing<br />
Leukonychia<br />
Palmer erythema<br />
Dupytren contracture<br />
Astrexis<br />
Juindice<br />
Pallor<br />
Xantholasma<br />
Parotid enlargment<br />
Fetor hepaticus<br />
Bruising &#038; Ecchymosis<br />
Spider nevi<br />
Gynecomastia<br />
Loss of  body hair (males)<br />
Ascitis<br />
Scratch marks<br />
Caput medosa<br />
Spleenomegaly<br />
Liver may be enlarged or cirrhotic<br />
Testicular atrophy<br />
Lower limb edema</p>
]]></content:encoded>
	</item>
	<item>
		<title>Comment on Causes of Chronic Liver Disease by Magoda</title>
		<link>http://4mrcp.com/?p=860&#038;cpage=1#comment-6762</link>
		<dc:creator>Magoda</dc:creator>
		<pubDate>Sat, 24 Oct 2009 21:19:31 +0000</pubDate>
		<guid isPermaLink="false">http://4mrcp.com/?p=860#comment-6762</guid>
		<description>Stigmata of Chronic Liver Disease:

1. spider nevi
2. palmar erythema
3. jundice
4. gynecomastia
5. ascitis
6. encephalopathy
7. asterixis ( flapping tremor )</description>
		<content:encoded><![CDATA[<p>Stigmata of Chronic Liver Disease:</p>
<p>1. spider nevi<br />
2. palmar erythema<br />
3. jundice<br />
4. gynecomastia<br />
5. ascitis<br />
6. encephalopathy<br />
7. asterixis ( flapping tremor )</p>
]]></content:encoded>
	</item>
	<item>
		<title>Comment on Crohn&#8217;s Disease and Ulcerative Colitis by Rajy</title>
		<link>http://4mrcp.com/?p=851&#038;cpage=1#comment-6761</link>
		<dc:creator>Rajy</dc:creator>
		<pubDate>Sat, 24 Oct 2009 19:33:27 +0000</pubDate>
		<guid isPermaLink="false">http://4mrcp.com/?p=851#comment-6761</guid>
		<description>&lt;p&gt;Gallstones is more common in patients with crohn&#039;s disease than in ulcerative colitis&lt;/p&gt;</description>
		<content:encoded><![CDATA[<p>Gallstones is more common in patients with crohn&#8217;s disease than in ulcerative colitis</p>
]]></content:encoded>
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